The University of Pittsburgh's Drug Discovery Institute (UPDDI) is developing and implementing a web-based Microphysiology database (MPS-Db) for the capture and analysis of data from various microphysiological organ models as part of the Tissue-Chip-Testing-Center program sponsored by NCATS.
The requirements for the database include aggregation, analysis, and management of MPS data; integration of MPS data with human and animal exposure data; and the evaluation of MPS results with respect to a reference and clinical data. The MPS-Db was designed and developed to provide user access through the Internet and to access and retrieve relevant data from other Internet databases. We will be extending the MPS-Db to support the development of microphysiological disease models under the Disease Modeling and Efficacy Testing (MPS-DMET) program, also sponsored by NCATS.
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